Protein Modification Reagents
Worthington Biochemical Corporation TRYPSIN TPCK TREATED 1G
A chromatographically purified, diafiltered, lyophilized powder that has been treated with L-(tosylamido-2-phenyl) ethyl chloromethyl ketone (TPCK) to inhibit contaminating chymotryptic activity [Kostka and Carpenter, J. Biol. Chem. 239, 1799 (1964)].
Medchemexpress LLC DBCO-PEG4-NHS ester | 1427004-19-0 | 99.0% | C34H39N3O10 | 500 MG
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC)
Abcam Recombinant human Prolyl Endopeptidase protein, 20UG
Recombinant human Prolyl Endopeptidase protein is a Human Full Length protein, in the 2 to 710 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, FuncS.
Protein/ Peptide/ Enzyme Synonyms: PEP, PREP, Prolyl endopeptidase, PE, Post-proline cleaving enzyme
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC DBCO-PEG2-acid | 2304558-25-4 | >=95.0% | C26H28N2O6 | 50 MG
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs themselves are composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, allowing PROTACs to exploit the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features a DBCO group for SPAAC
- Reacts with azide-containing molecules
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules M-PEG3-TOS | AstaTech | 50586-80-6 | MFCD13184964 | 274.330 | C12H18O5S | 95.000 | COCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 402181567
M-PEG3-TOS | AstaTech | 50586-80-6 | MFCD13184964 | 274.330 | C12H18O5S | 95.000 | COCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 402181567
Medchemexpress LLC S-(2-carboxyethyl)-L-cysteine | 4033-46-9 | MFCD03424208 | 98.6% | 193.22 g·mol⁻1 | C6H11NO4S | 10 MG
S-(2-Carboxyethyl)-L-cysteine is an amino acid-derived research reagent provided as a solid for biochemical and pharmacological studies that require a cysteine derivative. The compound is characterized with analytical data to support research use and is offered in small quantities for laboratory experiments.
- High purity: 98.6%.
- Chemical formula: C6H11NO4S.
- Molecular weight: 193.22 g·mol⁻1.
- Physical form: solid; soluble in water at 5 mg/mL with ultrasonic assistance.
- Available sizes: includes 10 mg and 25 mg; larger sizes available by quote.
- Supporting documents: data sheet, COA, SDS, HNMR, RP-HPLC, MS.
![Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2675364-08-4 | 98.1% | 475.53 g/mol | C24H33N3O7 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204498.png-250.jpg)
Medchemexpress LLC 5,8-dioxa-2,11-diazatetradecanoic acid bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2675364-08-4 | 98.1% | 475.53 g/mol | C24H33N3O7 | 50 MG
BCN-endo-PEG2-maleimide is an ADC linker containing PEG spacer units, an endo-BCN strained cyclooctyne moiety, and a maleimide reactive group used for bioconjugation and click-chemistry applications. It is employed in antibody-drug conjugate research to attach payloads to azide- or thiol-containing partners, and is reported to be an oil with high purity.
- Used as an ADC linker and for click-chemistry conjugations
- Contains endo-BCN for rapid bioorthogonal reaction with azides
- Features a maleimide group for thiol-reactive conjugation
- Reported purity approximately 98.1% and appears as an oil
- Store protected from light; in solvent: -80°C (6 months), -20°C (1 month)
Medchemexpress LLC m-PEG20-alcohol 25mg
m-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Kyfora Bio DSPE 25 MG
DSPE (1,2-Distearoyl-rac-glycero-3-Phosphatidylethanolamine) is a saturated zwitterionic phospholipid and a derivative of phosphatidylethanolamine. It can be used in liposomal drug and gene delivery formulations. DSPE can be conjugated with PEG or PCB to develop stealth liposomes that have extended circulation time in the bloodstream.Key application(s): LNP, stealth liposomes